http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-578511-A5
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e9445e5e3626f36e932c6451a928250 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C273-1854 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C273-18 |
| filingDate | 1972-06-08^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1976-08-13^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CH-578511-A5 |
| titleOfInvention | 1-(p-(acylaminovinyl)phenoxy) 2-hydroxy-3-aminopropanes beta - adrenergic block agents |
| abstract | Title cpds are of formula ArOCH2CHOHCH2NHR5 (I), (where Ar= II; R' = 1-7C alkyl, 1-7C alkoxy, or opt. substd. NH2; R2 = H or 1-7C alkyl, R3 = H, 1-7C alkyl, CO2H or CO2 (1-7C alkyl), R4 = H or 1-7C alkyl; R5 = 1-7C alkyl opt. substd. by CO2H or a CO2H deriv. or 7-12C alkylaryl opt. substd. in the aryl gps. by 1-7C alkyl, 1-7C alkoxy, hal or CF3; and R6 = H, hal CF3, 1-7C alkyl, 2-7C alkenyl, 1-7C alkoxy, 2-7C alkenyloxy, NO2, CH2O (1-7C alkyl), carbamoyl, N-(1-7C alkyl), carbamoyl, CN, or l. alkinyl-oxy; and salts of (I). (I) are prepd. by standard methods e.g. reaction of ArOCH2CHX'CH2Z' with Z2R5 and a base, where X' = OH and Z' = NH2 and Z2 a labile ester on vice versa, or X' + Z' = epoxy and Z2 = NH2. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0238868-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0238868-A3 |
| priorityDate | 1972-06-08^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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