Compounds derived from spirocyclic heterocycles substituted by substituted quinazoline-linked ethers; pharmaceutical composition; pharmaceutical combination; and use in the treatment of lung and respiratory diseases, autoimmune disease, allergic diseases and cancer, among others.
COMPOUNDS OF THE GENERAL FORMULA (I) WHERE A, RA, RB, RC, RD, ARE AS DEFINED IN THE DESCRIPTIVE MEMORY AND CLAIMS SPECIFICATIONS; PHARMACEUTICAL COMPOSITION; PHARMACEUTICAL COMBINATION; AND USE IN THE TREATMENT OF PULMONARY AND RESPIRATORY DISEASES, AUTOIMMUNE DISEASE, ALLERGIC DISEASES AND CANCER, AMONG OTHERS.