| abstract |
There is provided using in osteoclast the detection method of the abnormal bone metabolism of the gene of strongly expressed, with abnormal bone metabolism treat and/or preventive effect compound screening technique and treatment and/or prevention abnormal bone metabolism medical composition.The detection method for the abnormal bone metabolism that index is expressed as with the genes of people Siglec 15 is provided, and offer is included with specific recognition people Siglec 15, and suppress pharmaceutical composition of active antibody of osteoclast formation etc.. |