http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102002518-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P33-06 |
| filingDate | 2010-10-28^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68708861ea1df169549b3fbd59c47676 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccba8db7234cc05447afd4d4574289ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fcd296534e019ed2d3722f621875847c |
| publicationDate | 2011-04-06^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102002518-A |
| titleOfInvention | Method for preparing 7beta-hydroxyl-3beta cholesterol acetate from hydroxylase 3beta-cholesterol acetate |
| abstract | The invention relates to a method for preparing 7beta-hydroxyl-3beta cholesterol acetate, in particular to the method for preparing the 7beta-hydroxyl-3beta cholesterol acetate from hydroxylase 3beta-cholesterol acetate. The method comprises the following steps of: dissolving the hydroxylase 3beta-cholesterol acetate into a cosolvent; feeding the dissolved 3beta-cholesterol acetate solution in a buffer solution; adding an enzyme preparation and a hydrogen peroxide solution; adjusting the pH value to be 6-10; fully stirring and reacting at the temperature of 15-50DEG C for 0.5-9h; tracking and monitoring the reaction process by adopting a TLC (Thin-Layer Chromatography) silica gel plate or high performance liquid chromatography until the reaction is finished; extracting the reaction solution with an organic solvent; and removing the organic solvent by decompressing to obtain a crude product of the compound of the 7beta-hydroxyl-3beta cholesterol acetate. The invention has the advantages of mild and controllable reaction conditions, simple synthetic operation, low cost and high yield, and is friendly to the environment because a high-toxicity chemical reagent is removed. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021176066-A1 |
| priorityDate | 2010-10-28^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101220075-A |
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID467317676 |
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