http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102690325-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_437547aefa14c0cec2080ac0ad82d681 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-093 |
| filingDate | 2012-06-08^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-01-15^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d806e382aafb7be45779c8c3fadb7723 |
| publicationDate | 2014-01-15^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102690325-B |
| titleOfInvention | Synthesis of polypeptide PyroGlu-Pro-Arg-pNA.HCl |
| abstract | The invention discloses a synthesis method of developing a substrate PyroGlu-Pro-Arg-pNA.HCl, and belongs to the field of polypeptide synthesis. The synthesis method comprises the following steps of: condensing paranitroaniline and arginine of which guanidyl is protected by bis-Boc by using phosphorus oxychloride as a condensing agent; condensing the other two amino acids into dipeptide; and condensing the two synthesized peptide segments, and removing the protecting group bis-Boc of guanidyl by adopting HCl or a mixture of HCl and ethyl acetate to form the compound. The synthesis method has high yield, simple process and low preparation cost, and is suitable for preparation in batch. |
| priorityDate | 2012-06-08^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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