http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102718824-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3415a9c7cc3a12a39a4476288aab2987 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_31549ab70756d48304ab4b21a4e86627 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2012-06-20^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-03-04^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a1afca7f4a2c6b0bea98e31e795c2f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_201940165c1c708c560fae056f93fc76 |
| publicationDate | 2015-03-04^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102718824-B |
| titleOfInvention | Fluorine-containing water-soluble platinum complex for cancer treatment and preparation method thereof |
| abstract | The invention discloses a fluorine-containing water-soluble platinum complex for cancer treatment and a preparation method thereof. The complex is shown as Formula (I). Tests show that the water solubility of the platinum complex of the invention is one hundred times more than that of clinical drug oxaliplatin and that the stability of the platinum complex is also remarkably improved as compared with oxaliplatin. Drug effect experiments of animal models show that the complex of the invention is also better than oxaliplatin as for the effect of inhibiting cancers for a long term, thereby fully indicating the cancer-targeted effect. The platinum complex provided by the invention not only can solve the problem of poor preparation stability and the defect of inconvenience in clinical use of existing platinum drugs caused by lack of water solubility, but also can improve the effect of cancer treatment for existing clinical drugs. |
| priorityDate | 2011-06-24^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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