http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102787147-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-12 |
| filingDate | 2012-08-31^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-10-08^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2014-10-08^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102787147-B |
| titleOfInvention | Method for preparing L-dihydroorotate by enzymatic method |
| abstract | The invention discloses a method for preparing L-dihydroorotate by an enzymatic method. The method includes the steps: taking cyanate, L-aspartic acid and aspartate as raw materials and reacting the raw materials under an alkaline condition to form N-carbamoyl-L-aspartic acid; catalyzing the N-carbamoyl-L-aspartic acid by dihydroorotase or a thallus containing the dihydroorotase serving as a catalyst under a weak acid condition to prepare L-dihydroorotate by means of cyclization; and separating, concentrating and crystallizing obtained dihydroorotate enzymatic conversion solution to obtain the L-dihydroorotate. The N-carbamoyl-L-aspartic acid is catalyzed by the dihydroorotase, a raw material preparation and reaction system is simple, products are easily separated, the shortcoming of difficulty in obtaining raw materials in a chemical synthesis method is avoided, and the dihydroorotase is high in activity and short in reaction time. |
| priorityDate | 2012-08-31^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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