http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103183697-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
| filingDate | 2013-02-26^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-08-26^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-08-26^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103183697-B |
| titleOfInvention | Based on bigeminy heterocycle and near infrared fluorine boron two azole compounds of pyrrole group and method for making thereof and purposes |
| abstract | One class is based on the near infrared fluorine boron two azole compounds (BODIPY) of bigeminy Thienopyrroles group, and it has following structure:n wherein substituting group M, N, P, E, F, M ', N ', P ', E ' or F '=H or Br.The present invention has synthesized the BODIPY photosensitizers that bigeminy Thienopyrroles is the large conjugation of parent first, the introducing of two thienyl groups makes the absorption spectrum Einstein shift of this kind of photosensitizers arrive 680-720nm, emission peak 716n-750nm, be in the scope interior (650-900nm) of biological window, the fluorescence quantum efficiency of this dyestuff is higher simultaneously.This photosensitizers molar absorptivity is in the solution up to 200000M in additionn -1 cmn -1 .And the S in two thienyl groups is heavy atom, this just makes the triplet state efficiency of this photosensitizers increase, and then improves the efficiency that it produces singlet oxygen, and therefore, it has tempting application prospect in bio-imaging and optical dynamic therapy. |
| priorityDate | 2013-02-26^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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