http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103570639-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-20
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-20
filingDate 2012-08-08^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-02-03^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2016-02-03^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103570639-B
titleOfInvention A kind of synthetic method of Linezolid
abstract A kind of with the fluoro-4-morpholinyl of (S)-N-((3-(3-) phenyl)-2-oxo-5-oxazolidinyl) methyl) phthalic imidine is for raw material, at first suction filtration removing solid rear with hydrazine hydrate reaction, after again filtrate is concentrated with water and dichloromethane extraction complete, concentrated, after 30 DEG C-110 DEG C concentrated water outlets and methylene dichloride, the synthetic method of Linezolid is prepared add a large amount of toluene in concentrated solution after again with acetic anhydride.The method compared with prior art, can prepare more high purity, the Linezolid of higher yield, greatly can reduce the cost of large-scale industrial production Linezolid, simultaneously environmental friendliness.
priorityDate 2012-08-08^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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