http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103936680-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-42 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-42 |
| filingDate | 2014-04-18^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-08-24^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-24^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103936680-B |
| titleOfInvention | The preparation method of rosuvastain calcium known impurities |
| abstract | The present invention relates to the preparation method of rosuvastain calcium known impurities; with 4 (4 fluorophenyl) 5 triphenyl phosphorus bromine 6 isopropyl 2 ［ (N methyl N methylsulfonyl amido) ］ pyrimidine as raw material; reacted by witting, be acidified, aoxidize, alkaline hydrolysis, salt-forming reaction; preparation (double [E 7 [4 (4 fluorine-based phenyl) 6 isopropyl 2 [methyl (mesyl) amino] pyrimidine 5 base] 3R 3 hydroxyl 5 oxo 6 heptenoic acid] calcium salt), i.e. rosuvastain calcium known impurities.Its synthetic route is short, simple to operate, and products obtained therefrom purity is high, can be applicable to research of the chemical standard product. |
| priorityDate | 2014-04-18^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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