http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104147615-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f90c1df3857ee72900e0015c75caecd9 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 |
| filingDate | 2014-07-22^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4975f9e1e1d38b33e051373c15d7c9dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4415329c1dca16b88828e78208b61369 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_775e3cbf8e34b7bd2dfda0e6337a29d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1be58546280156f7533ea4dc3bce7bd8 |
| publicationDate | 2014-11-19^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104147615-A |
| titleOfInvention | Application of small RNA miR-20b in preparation of anti-inflammatory medicine |
| abstract | The invention relates to an application of small non-coded RNA genes miR-20b in preparation of an anti-inflammatory medicine. An inflammatory reaction is mainly caused by reactive Th17 cells which widely participate and play important pathogenic actions. The genes miR-20b have low specific expressions in the reactive Th17 cells; after miR-20b simulated bodies are respectively transfected into na.ve CD<4+>T cells or the negative control of the genes miR-20b is carried out, the miR-20b simulated bodies can be used for obviously reducing expressions of a gene level and a protein level of cytokine interleukin 17A, and the levels of proliferation and apoptosis of the Th17 cells are not changed by the genes miR-20b. Thus, the results show that the genes miR-20b can be used for effectively inhibiting differentiation of the Th17 cells and does not depend on the regulation and control of the numbers of cells. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108690123-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106191236-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105879061-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108690123-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106191236-A |
| priorityDate | 2014-07-22^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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