http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104817453-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-347 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-347 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C61-04 |
| filingDate | 2015-05-14^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-08-31^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-31^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104817453-B |
| titleOfInvention | A kind of method synthesizing cyclopropanecarboxylic acid |
| abstract | The invention discloses a kind of new method synthesizing cyclopropanecarboxylic acid; it includes, the preparation of reactant liquor system: under nitrogen protection, and 1～1.5mol zinc bits polishing being dried add in the first solvent; at 0～60 DEG C, add chloroacetic chloride or add stannous chloride activation 0.5～5 hour; after having activated, at 10～100 DEG C, drip the 2 of 1mol, 3 dibromo-propionic acids or 2; 3 dibromo-propionic acid derivatives; after dropping, insulation backflow 2～6 hours, it is cooled to 0～80 DEG C；Reaction preparation: under nitrogen protection, 0.9～1.2mol methylene triphenyl phosphine is dissolved in the first solvent of 2～6 equivalents and drops in described reactant liquor system by insulation, is progressively warming up to backflow, prepares cyclopropanecarboxylic acid.The present invention by three original steps, four, five-step approach shorten to a step complete reaction, greatly reduce the equipment investment in production and personnel and public work cost. |
| priorityDate | 2015-05-14^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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