http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104844500-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-584 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-48 |
filingDate | 2015-05-06^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-07-07^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-07-07^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104844500-B |
titleOfInvention | The method that a kind of one pot of fusion method of solid phase prepares amikacin intermediate |
abstract | The invention discloses the method that a kind of one pot of fusion method of solid phase prepares amikacin intermediate, comprising:Catalyst, phthalic anhydride and L α hydroxyl gamma aminobutyric acids are heated to melting, reaction is completed, and post processing obtains amikacin intermediate:(S) α hydroxyls γ N phthaloylamino butyric acid.The method is reacted using solvent-free solid-phase, it is not necessary to which the L HABA of high-purity, easy to operate, high income, chemical purity and optical purity are high, and the reaction time is short, is post-processed simple and easy to apply.If during using solid catalyst such as alkali alumina or weak-base ion-exchange resin, could be with recycled after catalyst upon activation.With fine industrial production prospect. |
priorityDate | 2015-05-06^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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