http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105349652-B

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Predicate Object
classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-154
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883
filingDate 2015-11-20^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-12-14^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-12-14^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105349652-B
titleOfInvention Molecular labeling and its application of the Steroidgenesis factor 1SF-1 promoter region hyper-methylation as intrauterine growth retardation
abstract The invention discloses the kit that can be used for detecting 1 SF-1 promoter zone methylation degree of the Steroidgenesis factor relevant to intrauterine growth retardation and its applications, the kit includes a pair of of 1 SF-1 promoter zone methylation specificity amplification primer of the Steroidgenesis factor, wherein the nucleotide sequence of upstream primer is as shown in SEQ ID NO.1, and the nucleotide sequence of downstream primer is as shown in SEQ ID NO.2.Advantage is that the diagnostic kit can be convenient the detection quickly realized on a molecular scale to intrauterine growth retardation, and only need to carry out by parent blood, avoids causing to damage to fetus;It is sensitive, early stage that DNA methylation modification mode, which changes as the advantage of marker, special, simultaneously because hereditability and invertibity that DNA methylation is modified, can provide guidance for the early treatment of birth defect.The present invention provides new biomarker for IUGR pregnancy period sieving and diagnosis.
priorityDate 2015-11-20^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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