http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105505884-B

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-107
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-32
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
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filingDate 2016-01-26^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-10-03^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2017-10-03^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105505884-B
titleOfInvention Carry out recombination system and the application of antibody expression and assembling
abstract The invention belongs to molecular biology and DNA techniques field, specifically related to antibody expression and assembling recombination system and application, a kind of carrier for expression of eukaryon for expressing heavy chain of antibody and light chain is disclosed, the purpose is to provide a kind of recombinant eukaryon expression vector and its construction method, is easy to express each antibody-like.The invention also discloses the application of pRTL1 HC and pRTL1 LC above-mentioned carrier for expression of eukaryon.The present invention is based on the carrier for expression of eukaryon for expressing IgG antibody heavy chain and light chain, being further able to expression includes the antibody of all kinds of difference in functionalitys such as IgG antibody, Fab antibody, Fv antibody, humanization ScFv Fc antibody and mouse/people's chimeric antibody, the expression efficiency of the fragments such as antibody expression Fv, Fab and ScFv is favorably improved, important reference is provided for the antibody of being capable of the various difference in functionalitys of successful expression.
priorityDate 2016-01-26^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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