http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105646391-B

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D271-113
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D271-113
filingDate 2016-03-07^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-12-12^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2017-12-12^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105646391-B
titleOfInvention Dihydroxyl quaternary ammonium salt of oxadiazoles heterocyclic substituted with bacteriostatic activity and preparation method thereof
abstract The present invention relates to a kind of dihydroxyl quaternary ammonium salt of oxadiazoles heterocyclic substituted with bacteriostatic activity and preparation method thereof, belong to antibacterial material and preparation method thereof technical field.Preparation method:Reacted by N R1 diethanol amine and halogenated hydrocarbons in organic solvent, after precipitating reagent precipitation, be recrystallizing repeatedly so as to obtain the dihydroxyl quaternary ammonium salt (N R1 N R2 N, N dihydroxy ethyls ammonium halide) of oxadiazoles heterocyclic substituted.The quaternary ammonium salt synthesis of the present invention is simply, yield is high, reaction is fast, cost is low, method of purification is easy.The dihydroxyl quaternary ammonium salt of the oxadiazoles heterocyclic substituted of the present invention is respectively provided with preferable bacteriostasis to fungies such as the various bacteriums such as staphylococcus aureus, Escherichia coli and Candida albicans, has good application prospect.
priorityDate 2016-03-07^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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