http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105646713-B

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-303
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1057
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-68
filingDate 2014-01-22^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-07-12^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-07-12^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105646713-B
titleOfInvention A kind of monoclonal antibody and its application
abstract The invention discloses a kind of variable region sequences with the monoclonal antibody and the monoclonal antibody that neutralize human leukocytes differentiation antigen CD24 bioactivity.The present invention is using Antigenic Peptide and limpet hemocyanin conjugate CD24-KLH as immunogene, inoculation BALB/c mouse, it takes immune Mouse spleen cells and merges it with myeloma cell, the hybridoma cell strain that can express anti-CD24 antibody is obtained, this cell strain can be used for preparing anti-CD24 monoclonal antibody.The present invention has cloned anti-CD24 antibody variable region amino acid sequence simultaneously.Anti- CD24 antibody of the invention can be specifically bound with CD24, therefore be can be used for treating and expressed excessive, abnormal, relevant disease out of control to CD24.
priorityDate 2014-01-22^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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