abstract |
The present invention relates to novel 7β-hydroxysteroid dehydrogenases obtained from bacteria of the genus Collinsella, in particular the strain Collinsella aerofaciens, sequences encoding said enzymes, methods for producing said enzymes , and their use in the enzymatic conversion of cholic acid compounds, and in particular in the production of ursodeoxycholic acid (UDCA); the present invention also relates to a new method for the synthesis of UDCA. |