| abstract |
The invention belongs to the technical field of composite materials, and discloses a xylan-based double-network nanocomposite hydrogel and its preparation and application. The method is (1) adding graphite oxide powder into deionized water and ultrasonically dispersing to obtain a GO water dispersion; (2) adding xylan to deionized water and heating and stirring to obtain a xylan solution; (3) adding Water-soluble calcium salt, reaction monomer and xylan solution are added to the GO water dispersion, under ice bath conditions, stirring and dispersing evenly, adding initiator, crosslinking agent and accelerator, stirring and mixing evenly to obtain a mixed solution; ( 4) drying the mixed solution in step (3) to obtain a xylan-based double network nanocomposite hydrogel. The composite hydrogel obtained by the invention has relatively high mechanical properties, is biodegradable, and has good biocompatibility, and is applied in the field of biomedicine, such as tissue engineering, drug sustained release, cell culture scaffold, cartilage tissue, and the like. |