| abstract |
The present invention has synthesized a series of trifluoromethoxy reagent precursor, and the trifluoromethoxy silver of high activity can be obtained under conditions of activating reagent.Utilize the invention thinking, by the way that brominated reagent is added, the silver salt and trifluoromethoxy reagent and activating reagent of catalytic amount, the bromo trifluoromethoxy compound such as following formula (I) can be efficiently synthesized from the olefines substrate being easy to get, meanwhile chiral catalyst can be realized asymmetric reaction.Especially such compound can be as intermediates such as medicine, pesticide, materials.Further, under certain conditions, bromo trifluoromethoxy compound provided by the present invention can obtain the product of different functional groups derivative. |