http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106361736-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-325 |
| filingDate | 2015-07-24^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-02-07^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-02-07^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106361736-B |
| titleOfInvention | Application of a kind of guanidine compound |
| abstract | The present invention discloses the application of a guanidine-based compound as shown in formula I or a pharmaceutically acceptable salt thereof in the preparation of a medicine for treating degenerative diseases of the nervous system; wherein, the R is hydrogen, carboxyl or -C 1 ~C 5 alkyl-carboxy. The guanidine-based compound of the present invention has significant effects on the protective effect of hydrogen peroxide-induced hippocampal nerve cell damage in neonatal rats and the inhibitory effect on β-amyloid protein aggregation in vitro, and has potential clinical application value. |
| priorityDate | 2015-07-24^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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