http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106478803-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-575 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 |
| filingDate | 2016-10-20^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-12-20^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-12-20^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106478803-B |
| titleOfInvention | Peptide for promoting insulin release of hypsizygus marmoreus, gene thereof and application thereof in pharmacy |
| abstract | The invention relates to a hypsizygus marmoreus insulinotropic peptide, a gene thereof and application thereof in pharmacy, wherein the hypsizygus marmoreus insulinotropic peptide is a cyclic peptide consisting of 33 amino acids, the molecular weight is 3535.14 daltons, the isoelectric point is 10.3, the amino acid sequence of the hypsizygus marmoreus insulinotropic peptide is shown in SEQ ID NO.1, and the fourth cysteine and the ninth cysteine of the peptide are in intra-molecular disulfide bond. The gene sequence of the hypsizygus marmoreus insulinotropic peptide consists of SEQ ID NO.4, wherein the gene sequence coding the functional mature hypsizygus marmoreus insulinotropic peptide is 379-477 nucleotides. The mature functional polypeptide amino acid sequence of the hypsizygus marmoreus insulin-releasing peptide is deduced from the gene of the hypsizygus marmoreus insulin-releasing peptide, and the synthesized hypsizygus marmoreus insulin-releasing peptide has good insulin release promoting effect, has the advantages of cytotoxicity, no plasma coagulation activity and the like, and can be applied to preparation of medicaments for treating diabetes. |
| priorityDate | 2016-10-20^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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