http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106727432-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5161 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 |
| filingDate | 2017-03-07^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-05-31^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-05-31^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106727432-B |
| titleOfInvention | A kind of Prussian blue analogue nano particle and the preparation method and application thereof |
| abstract | The invention discloses a kind of Prussian blue analogue nano particle, which is coated on nano grain surface and is formed by Prussian blue analogue nano particle as kernel, organic polymer surface protectant polyvinylpyrrolidone/chitosan and hyaluronic acid.Above-mentioned Prussian blue analogue nano particle the preparation method comprises the following steps: S1, preparation containing zinc salt, ferrous sulfate, molysite and organic polymer surface protectant mixed solution；S2, after being stirred at room temperature 30 minutes to 2 hours, solution is put into the bag filter equipped with distilled water and is dialysed two days；S3, solid matter is pulled out, solid product is collected by freeze-drying.Above-mentioned Prussian blue analogue nano particle is applied in targeting cancer therapy.Zn-FePB NPH drug of the present invention is very safe；By displacing the copper in cancer cell, can achieve the purpose that " to die of hunger " cancer cell；And the present invention by hyaluronic acid have high targeting on the basis of carry out PVP (or chitosan) doping can it is better regulation nanoparticle size. |
| priorityDate | 2017-03-07^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Showing number of triples: 1 to 65 of 65.