http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107119111-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-9126 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 |
| filingDate | 2017-03-28^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-02-12^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-02-12^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107119111-B |
| titleOfInvention | DNA molecule layer-by-layer self-assembly microcapsule wrapped by DNase and preparation and application thereof |
| abstract | The invention discloses a DNA molecule layer-by-layer self-assembly microcapsule wrapped by DNase and preparation and application thereof, wherein the microcapsule takes carbonate particles as a template core, a polyacrylamide hydrochloride layer and an oligonucleotide chain a layer are sequentially wrapped outside the carbonate particles, then a plurality of oligonucleotide chain b layers and oligonucleotide chain c layers are alternately wrapped, and the template core is removed by EDTA to prepare the DNA molecule layer-by-layer self-assembly microcapsule; and finally, incubating the DNA molecule layer by layer self-assembly microcapsule, the oligonucleotide chain d and the heme together to form the DNA molecule layer by layer self-assembly microcapsule wrapped by the DNase. The outer layer of the microcapsule is a layer-by-layer self-assembled DNA chain, and the specific DNA chain has molecular recognition and DNase catalysis functions, so the microcapsule has potential targeting effect and self-tracing capability, and has definite application prospect in the aspects of targeting recognition and detection. |
| priorityDate | 2017-03-28^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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