http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107543808-A

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filingDate 2017-07-12^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca8b2724e04e821ed414139b97cf077d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9985d7b04d59cf0652357ac33ec8285c
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publicationDate 2018-01-05^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107543808-A
titleOfInvention A kind of ratiometer nano-probe of hydrogen peroxide response and its application
abstract The present invention disclose ratiometer nano-probe and its application of a kind of hydrogen peroxide response, and the probe includes the fluorescence molecule that hydrogen peroxide responds, the inert fluorescence molecule of hydrogen peroxide and the good polymer of biocompatibility.Invention additionally discloses application of the ratiometer nano-probe of hydrogen peroxide response in malignant solid tumor Peripheral Circulation tumour cell detection agent is prepared.Ratiometer nano-probe provided by the invention has good water solubility, easily by cellular uptake and cytotoxicity it is low, the quantitative imaging for the hydrogen peroxide in circulating tumor cell.The ratiometer nano-probe has excellent fluorescence property, has good sensitivity and specificity to hydrogen peroxide, can detect in different malignant entity oncocytes the difference of hydrogen peroxide level and the into the cell difference for the amount of taking the photograph.
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priorityDate 2017-07-12^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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