http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108148025-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_008c9107ff464e201e724ad32b7630cc |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-048 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-68 |
filingDate | 2016-12-05^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b07efb2a60521ccf0315ddb1c3709094 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c0a1714be3177256db4896882c1396f |
publicationDate | 2018-06-12^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108148025-A |
titleOfInvention | A kind of 5-alkylthio polysubstituted furan derivative and its synthesis method |
abstract | The invention discloses a method for synthesizing 5-alkylthio polysubstituted furan derivatives with potential biological activity. Using 3,3-dialkylthio-2-propene-1-one and β-carbonyl compounds (β-ketoester, β-diketone) as raw materials, which are easy to prepare, have structural diversity and multiple reaction centers, through molecular The inter-oxidative cross-coupling and intramolecular cyclization reactions generate 5-alkylthio multi-substituted furan derivatives in one step. The multi-substituted furan derivatives have certain potential pharmaceutical activities and can be further transformed into functionalized products. The method has easy-to-obtain raw materials, simple operation, mild synthesis reaction conditions, high reaction efficiency, and diverse functional groups. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114380777-A |
priorityDate | 2016-12-05^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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