| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-222
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-224
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7036
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-224
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-222 |
| filingDate |
2016-09-02^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2022-06-10^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2022-06-10^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-108350014-B |
| titleOfInvention |
Aminoglycoside derivatives and their use in the treatment of genetic disorders |
| abstract |
The present invention provides a variety of novel aminoglycosides as shown in formulae Ia and Ib as defined in this specification, designed to exhibit read-through activity of stop codon mutations. The present invention also provides various pharmaceutical compositions comprising the novel aminoglycosides, and uses thereof in the treatment of multiple genetic diseases and multiple conditions, the multiple genetic diseases and multiple conditions For example: multiple disorders and multiple diseases associated with stop codon mutations. |
| priorityDate |
2015-09-02^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |