| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2325-08 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F212-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G81-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J9-141
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F8-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J9-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-265
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J9-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J13-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F212-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G81-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J9-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J13-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J9-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F212-36 |
| filingDate |
2018-05-04^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2020-11-10^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2020-11-10^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-108586794-B |
| titleOfInvention |
Immune adsorbent for rheumatoid factor for blood perfusion and preparation method thereof |
| abstract |
An immunoadsorbent of rheumatoid factor for hemoperfusion and its preparation method are provided. The immunoadsorbent is prepared by taking chloromethylated styrene-divinylbenzene resin with a macroporous structure as a carrier, small molecular polypeptide (consisting of 6-14 amino acids) as a ligand and amino-functionalized polyethylene glycol (H) with different molecular weights 2 N‑PEG‑NH 2 ) Acting as an arm, thereby coupling the carrier microspheres with the ligand via the arm. The immunoadsorbent is simple to prepare, avoids the potential immunogenicity and other related side effects of a macromolecular (antigen or antibody) ligand immunoadsorbent on the basis of keeping the specific adsorption of the rheumatoid factors, has low cost, and is suitable for removing the excessive rheumatoid factors in a patient body by blood or plasma perfusion. |
| priorityDate |
2018-05-04^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |