http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108623583-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04
filingDate 2018-05-04^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-01-15^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-01-15^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108623583-B
titleOfInvention Preparation method of iridium-catalyzed moxifloxacin side chain intermediate
abstract The invention discloses an iridium-catalyzed preparation method of a moxifloxacin side chain intermediate, which comprises the following steps: under the catalysis of a chiral catalyst, 6-benzyl-pyrrolo [3,4-b ] pyridine-5, 7-diketone and hydrogen are subjected to asymmetric hydrogenation reaction in an organic solvent to obtain the (1S,6R) -8-benzyl-7, 9-dioxo-2, 8-diazabicyclo [4,3,0] nonane. The preparation method has the advantages of high efficiency, strong substrate universality and high enantioselectivity, and has wide application prospect in the fields of asymmetric synthesis and medicine research and development.
priorityDate 2018-05-04^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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