http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108623583-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
filingDate | 2018-05-04^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-01-15^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-01-15^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108623583-B |
titleOfInvention | Preparation method of iridium-catalyzed moxifloxacin side chain intermediate |
abstract | The invention discloses an iridium-catalyzed preparation method of a moxifloxacin side chain intermediate, which comprises the following steps: under the catalysis of a chiral catalyst, 6-benzyl-pyrrolo [3,4-b ] pyridine-5, 7-diketone and hydrogen are subjected to asymmetric hydrogenation reaction in an organic solvent to obtain the (1S,6R) -8-benzyl-7, 9-dioxo-2, 8-diazabicyclo [4,3,0] nonane. The preparation method has the advantages of high efficiency, strong substrate universality and high enantioselectivity, and has wide application prospect in the fields of asymmetric synthesis and medicine research and development. |
priorityDate | 2018-05-04^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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