http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109320482-B

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-58
filingDate 2018-11-20^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-03-29^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-03-29^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-109320482-B
titleOfInvention Synthetic method of alpha-substituted 2H-chromene derivative
abstract The invention discloses a synthetic method of an alpha-substituted 2H-chromene derivative, which takes 2H-chromene acetal and beta-ketoacid as raw materials, takes water as a solvent, and is stirred at room temperature to obtain the corresponding 2H-chromene derivative. The synthetic method has simple reaction conditions, does not need special equipment, can carry out reaction at room temperature and in the atmospheric environment, and does not need heating and inert gas protection; the reaction byproducts are only carbon dioxide and ethanol, so the method is easy to purify and environment-friendly; the yield of the target compound is high and can reach 80-95%.
priorityDate 2018-11-20^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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