http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109680032-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P33-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-14 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-785 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-68 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P33-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P39-00 |
| filingDate | 2018-12-20^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-05-14^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-05-14^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-109680032-B |
| titleOfInvention | Method for synthesizing 7, 21-dihydroxy-20-methylpregna-4-en-3-one by using microorganisms |
| abstract | The invention provides a method for synthesizing 7, 21-dihydroxy-20-methylpregna-4-en-3-one by using microorganisms. The invention efficiently converts 4-HBC into 7 alpha-OH-4-HBC and 7 beta-OH-4-HBC by utilizing one or more fermentation liquids of mucor circinelloides, acremonium erectum, mucor racemosus and aspergillus fumigatus through a two-step fermentation method. Under the condition that the feeding amount of the substrate 4-HBC is 10-20g/L, the conversion rate is high, two products, namely 7 alpha-and 7 beta-hydroxy-4-HBC, are separated from the product, and the total yield of the product is 46.5-85.32%. The method has the advantages of simple operation, low cost and high yield, provides a new method for the development and synthesis of steroid drugs, and has good economic value. |
| priorityDate | 2018-12-20^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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