http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110093310-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-999 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-04 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0656 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 |
| filingDate | 2018-01-29^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-07-02^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-07-02^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110093310-B |
| titleOfInvention | Method for converting fibroblasts into immortalized cells and application thereof |
| abstract | The invention relates to a method for inducing fibroblast to be transformed into immortalized cell and application thereof. The method comprises the following steps: culturing the fibroblasts in a culture medium, adding a Myosin inhibitor into the culture medium, and continuing culturing until immortalized cells are obtained. The invention also relates to a culture medium for inducing the transformation of fibroblasts into immortalized cells. The method only needs single micromolecule or single factor treatment, has simple operation and good repeatability, can be carried out in vivo and in vitro efficiently, does not relate to transgene operation, has good safety of the obtained immortalized cells, is suitable for understanding the growth rule of the cells, exploring the aging reason of the cells and solving the problem of organ transplantation, can also lay a certain foundation for treating tumors and controlling the proliferation of tumor cells, and has important significance. |
| priorityDate | 2018-01-29^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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