| abstract |
It is dissipated the invention discloses a kind of Radix Astragali learned based on transcription and precisely intervenes hyperlipidemia biological marker object detecting method.The biomarker includes at least one of Acat2, Apoc4, Bhmt, Cyp51, Fads1, Fads2, Gnmt, Hmgcs1, Pemt, Cyp3a62, Egln3.The present invention is by transcript profile sequencing (RNA-Seq) Technology application into traditional Chinese medicine prevention lysis, the possible action target spot of disease preventing and treating is dissipated for extension ancient prescription Radix Astragali and molecular mechanism provides foundation, provides more laboratory references for its basic research and clinical application.The present invention is based on transcription groups to filter out the potential function gene that Radix Astragali dissipates lipid-loweringing, solves the problems, such as that Chinese herb prevention hyperlipidemia in the prior art, obesity and nonalcoholic fatty liver are ineffective. |