| abstract |
The present invention relates to methods for diagnosing heart disease by bacterial metagenomic analysis. More specifically, the present invention relates to the prediction of pathogenic factors and onset, early stage Methods for diagnosing heart disease and predicting prognosis. By using the metagenomic analysis of bacterial-derived extracellular vesicles of human-derived samples according to the present invention, the risk of heart disease is predicted in advance, so early diagnosis and prediction of heart disease risk groups. Therefore, with proper management, the onset of the disease can be delayed or prevented, and early diagnosis can be made even after the onset of the disease. Therefore, the incidence of heart disease can be reduced, and the therapeutic effect can be improved. In addition, by avoiding exposure to pathogenic factors through metagenomic analysis in patients diagnosed with heart disease, it can improve the prognosis of heart disease or prevent the recurrence of heart disease. |