abstract |
The invention provides a biological gel for a burn department for accelerating wound healing and a preparation method thereof. Firstly, carrying out oxidation reaction on bacterial nano-cellulose by adopting sodium periodate to prepare modified bacterial nano-cellulose; then dispersing the bacterial nano cellulose into water to prepare modified bacterial nano cellulose dispersion liquid, and mixing the modified bacterial nano cellulose dispersion liquid with a sodium alginate solution to obtain a mixed solution; then, mixing and stirring the mixed solution and the collagen swelling solution, and then placing the mixture in a mixed crosslinking aqueous solution of boric acid and calcium chloride for crosslinking reaction to prepare composite biogel; and finally, soaking the composite biogel in a polyhexamethylene hydrochloric acid solution to prepare the biogel for the burn department, which can accelerate wound healing. The biological gel for the burn department, which is used for accelerating the healing of the wound surface, has excellent stability and thermal reversible self-repairing performance, and also has excellent biocompatibility, water absorption swelling property and broad-spectrum antibacterial performance. |