| abstract |
The invention relates to a polyamino modified cyclodextrin method, which comprises the following preparation steps of polyamino modified cyclodextrin in parts by weight: (1) dispersing cyclodextrin into water, and slowly adding 10-15% of strong alkali aqueous solution into the water until the system is transparent to obtain a solution I; (2) adding p-toluenesulfonyl chloride and acetonitrile into a reactor, dropwise adding the solution I into the reactor, continuously reacting for 3-5 h at room temperature after dropwise adding is finished for 0.5-1 h, finishing the reaction and carrying out suction filtration, putting the filtrate into a refrigerator overnight, separating out a large amount of white precipitates, carrying out suction filtration to obtain white solids, dissolving the white solids with water, carrying out suction filtration, refrigerating the filtrate to separate out a large amount of white precipitates, filtering, and carrying out vacuum drying to obtain poly-6-p-toluenesulfonyl cyclodextrin; (3) dissolving poly-6-p-toluenesulfonyl cyclodextrin and polyamine in a dipolar solvent, reacting for 4-6 h at 50-80 ℃, adding glycidyl methacrylate, continuing to react for 2-4 h, cooling to room temperature, adding methanol, adding acetone for precipitation, performing suction filtration to obtain a white solid, and repeating the dissolution of methanol and the precipitation of acetone to obtain the polyamino modified cyclodextrin containing double bonds. |