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filingDate 2018-12-12^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d428bf154d6b94e246fa490f188647ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de9bda53f956baa2d3ebf09aa6188467
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publicationDate 2020-08-07^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111512143-A
titleOfInvention Methods and sensors for detecting the presence or absence of contaminants
abstract In one aspect, the present invention relates to a method of detecting contaminants in a measurement chamber (201) of a sample analyzer (200). The sample analyzer (200) comprises an optical sensor having a sensor layer (205) comprising a luminophore (201), wherein the sensor layer (205) has a sensor surface (206) forming access to a measurement chamber (201) ) interface. The method includes the steps of: filling a measurement chamber with a fluid sample; applying a stimulus to a luminophore in the sensor layer; detecting, as a function of time, luminescence emitted from the luminophore in the sensor layer in response to the stimulus; obtaining a measurement of the detected luminescence a time series of values; based on the time series, an actual value of the first parameter and an actual value of the second parameter are determined, wherein one of the first parameter and the second parameter refracts the interface between the sensor layer and the measurement chamber sensitive to changes in rate, and wherein the other of the first parameter and the second parameter is insensitive to changes in refractive index at the interface between the sensor layer and the measurement chamber; formulating the second parameter based on the actual value of the first parameter an expected value; comparing the expected value of the second parameter with the actual value of the second parameter; and determining the presence (or absence) of the contaminant based on the comparison. In another aspect, the present invention provides a sample analyzer configured to detect contaminants in a measurement chamber using an embodiment of the above-described method.
priorityDate 2017-12-22^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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