| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e58c26756b1d679b4ec7e34abb4942bc |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5254
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18521
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18532 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 |
| filingDate |
2020-12-09^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecbe041c284303f87c7ebdc2af1d062c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55b823485d2396d37f1143bdcddd258b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19323cc230c3b1fac91082c8caf2e0c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2fc8a2f7267d10e446b8ffe91645aee |
| publicationDate |
2021-03-16^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-112501134-A |
| titleOfInvention |
A human respiratory syncytial virus strain and application thereof |
| abstract |
The invention discloses a human respiratory syncytial virus strain and application thereof, and relates to the field of virus immunity. Four highly virulent mutant strains of human respiratory syncytial virus were obtained through continuous passage screening, and all of them were confirmed to be subtype A hRSV through gene sequence determination. The highly virulent mutant strain of human respiratory syncytial virus has good genetic stability and strong immunogenicity after immunizing animals. Therefore, the highly virulent mutant strain of human respiratory syncytial virus can be used for breeding of attenuated strains, screening of safe and effective attenuated strains with immune activity, can be applied to infect mice and cause the death of mice, thereby constructing a lethal type The hRSV infection animal model is used for the screening and evaluation of hRSV vaccines and anti-hRSV drugs. |
| priorityDate |
2020-12-09^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |