| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f5dfc0eed1db83b989cce292d784356 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6424 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2019-12-13^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb5f250b721b8dbab4d225515c843223
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c08eb46db4901a60cbab1b8156d45716
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d32594da34afed1d795eb0b037fdce9d |
| publicationDate |
2021-10-15^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-113507961-A |
| titleOfInvention |
FAP alpha specific bicyclic peptide ligands |
| abstract |
The present invention relates to polypeptides which are covalently bound to a molecular scaffold such that two or more peptide loops are subtended between the attachment points of the scaffold. In particular, the invention describes peptides that are high affinity binders for fibroblast activation protein a (FAP α). The invention also includes drug conjugates comprising the peptides conjugated to one or more effectors and/or functional groups, pharmaceutical compositions comprising the peptide ligands and drug conjugates, and uses of the peptide ligands and drug conjugates in preventing, inhibiting, or treating FAP α -mediated diseases or conditions. |
| priorityDate |
2018-12-13^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |