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filingDate 2020-06-02^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61c5a9128d325067eca060fcc9ed7ec4
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publicationDate 2022-03-11^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114174325-A
titleOfInvention Combination of engineered natural killer cells and engineered T cells for immunotherapy
abstract Several embodiments of the methods and compositions disclosed herein relate to immune cells engineered to express one of chimeric antigen receptors and/or genetically modified to enhance the efficacy of the immune cells in cellular immunotherapy or Many aspects. Several embodiments relate to genetic modifications that reduce potential side effects of cellular immunotherapy. In several embodiments, compositions of cells are used to achieve rapid and long-term tumor reduction with the potential to reduce or eliminate graft-versus-host effects.
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priorityDate 2019-06-04^^<http://www.w3.org/2001/XMLSchema#date>
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID7021830
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID24934
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP13726
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID9209431
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA2BTA0
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID18218237
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID18218234
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ673L6
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP07524
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA4QLJ4
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID14208651
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO72120
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA4QLA6
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