http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114657158-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y113-11052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0645 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0639 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0069 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0781 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0784 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0786 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2022-05-25^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-10-21^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-10-21^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114657158-B |
| titleOfInvention | IDO1 related vaccines and their applications |
| abstract | The present invention proposes an IDO1-related vaccine and its application. The IDO1-related vaccine includes: isolated polypeptides, isolated nucleic acids, antigen-presenting cells, immune cells and/or antibodies, and the isolated polypeptides have SEQ ID NO: 2 , 3, 5, 6, 8, 9, 11, 13-15, 18-20, 22-24, 26-28, 30, 32-36 amino acid sequence or functional analogs thereof. The vaccine of the invention can take the immunosuppressive protein IDO1 epitope as a target, improve the activity and number of anti-tumor immunosuppressive cells in the tumor microenvironment, and specifically remove negatively regulated cells such as stromal cells and immune cells in the tumor microenvironment, Tumor cells expressing IDO1 have high safety and are of great significance in the prevention and treatment of cancer. |
| priorityDate | 2022-05-25^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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