Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ecf4ab63a9f195c433dbd05f7ec4f5b4 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2002-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2004-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-57 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01F7-36 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01F7-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-29 |
filingDate |
2022-04-11^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0269607c26d4a53abecfc4d914385eaf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0d832019ec41f6eb3144a345ddf1950 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b741ba013d68ab98975d954cbe946ab0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9efc09ae3fd844674c1e0657ee619724 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bc9db054ba86e696782102d0b67d576 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cdfb84f4187ef7ec72bcac3be4492f97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_817239ff7c0e071a7849943ee4bc82d3 |
publicationDate |
2022-08-09^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-114870007-A |
titleOfInvention |
A kind of aluminum adjuvant with pseudo-boehmite structure and preparation method thereof |
abstract |
The invention discloses a preparation method of an aluminum adjuvant with a pseudo-boehmite structure. High-speed shearing followed by homogenization to obtain the aluminum adjuvant. The method of the invention improves the method for producing pseudo-boehmite by hydrolysis of aluminum alkoxide. In the process, only two raw materials, water and aluminum isopropoxide are used. The hydrolyzed product does not need to be baked or dissolved with acid, and the final product is A colloidal solution in a water-dissolved state. At the same time, the method has the advantages of low hydrothermal temperature, short hydrothermal time and simple process. What is more valuable as a vaccine adjuvant is that the aluminum adjuvant produced by this patent is more effective in inducing the same level of humoral immunity than the aluminum adjuvant prepared by the conventional precipitation method and the commercially available aluminum adjuvant with pseudo-boehmite characteristics. On the basis of , it can induce a higher level of cellular immunity and have better suspension stability. |
priorityDate |
2022-04-11^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |