http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114994231-A

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filingDate 2022-06-08^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-09-02^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114994231-A
titleOfInvention A kind of method for determining nitrite in rifampicin or rifapentine by ion chromatography
abstract The invention belongs to the technical field of drug detection, and in particular relates to a method for determining nitrite in rifampicin or rifapentine by ion chromatography, comprising the following steps: taking rifampicin or rifapentine crude drug, passing through methanol and After the diluent composed of deionized water is dissolved, use RP solid phase extraction column to remove impurities, and collect the 6mL of the subsequent filtrate as the test solution for use; take the blank sample diluent, and then add the nitrite standard solution to prepare different concentrations. The reference substance solution is for standby use; carry out the test solution and the reference substance solution of different concentrations under preset ion chromatographic conditions, respectively, make a standard curve according to the detection results of the reference substance solutions of different concentrations, and then according to The standard curve and the test results of the test solution were used to calculate the content of nitrite in the test solution. Using the method provided by the invention to determine the nitrite in rifampicin or rifapentine has good linearity, accuracy, limit of quantification and limit of detection.
priorityDate 2022-06-08^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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