| abstract |
The present invention provides a novel compound, which has an excellent effect of suppressing the generation of collagen and less side effects, with being excellent in terms of safety. The compound of the present invention is represented by the following general formula (1): [wherein X<1> represents a nitrogen atom or a group -CH=; R<1> represents a group -Z-R<6>, wherein Z represents a group -CO-, a group -CH(OH)-, or the like, and R<6> represents a 5- to 15-membered monocyclic, dicyclic, or tricyclic, saturated or unsaturated heterocyclic group having 1 to 4 nitrogen atoms, oxygen atoms, orsulfur atoms; R<2> represents a hydrogen atom, a halogen atom or a lower alkylene group; Y represents a group -O-, a group -CO-, a group -CH(OH)-, a lower alkylene group, or the like; and (A) represents a group or the like, wherein R<3> represents a hydrogen atom, a lower alkoxy group, or the like, p represents 1 or 2, and R<4> represents an imidazolyl lower alkyl group or the like. |