http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CO-6270235-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01ded0c730d7168677d30c83d61e01ab |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4738 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4733 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate | 2010-04-05^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f73da155fdd08ca60702f0232b82c03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eaf3484cada4a1015df0824199397768 |
| publicationDate | 2011-04-20^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CO-6270235-A2 |
| titleOfInvention | A PROISELT PEPTIDE SELECTED FROM AN N-TERMINAL, AMIDA AND CISTEINE ACETYLL GROUP |
| abstract | The embodiments relate to Prolslet peptides, preferably, HIP, which exhibit increased stability and efficacy, and methods to use them to treat a pathology associated with impaired pancreatic function, including type 1 and 2 diabetes and their symptoms. 1. A Prolslet peptide characterized in that it comprises an optimization modification, wherein said optimization modification is selected from the group consisting of an N-terminal acetyl group, a C-terminal amide group, and a C-terminal cysteine residue. 2. The peptide of claim 1, characterized in that said optimization modification is selected from the group consisting of (i) an N-terminal acetyl group and a C-terminal amide group and, (ii) an N-terminal acetyl group and a C-terminal cysteine residue. 3. The peptide of claim 1, characterized in that said peptide is a modified HIP1 peptide, a modified HIP2 peptide, or a modified HIP3 peptide. 4. The peptide of claim 1, characterized in that said peptide is a modified REG3A human peptide, a modified REG3G human peptide, a modified REG1A human peptide, a modified REG1B human peptide, a modified REG4B human peptide, a hamster INGAP peptide , a modified hamster REG2 peptide, a modified hamster REG3G peptide, a modified rat REG1 peptide, a modified rat PAP / REG3B peptide, a modified rat PAP3 peptide, a modified rat REG3G peptide, mouse REG 1G peptide modified, modified mouse REG2 peptide, modified mouse REG3A peptide, modified mouse REG3B peptide, modified mouse REG3G peptide, modified mouse REG3S peptide, modified mouse REG4 peptide, modified PTP bovine peptide. |
| priorityDate | 2007-08-30^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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