http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CY-1117612-T1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5fece74aa8c0cb73d997c194165159cc |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-00 |
| filingDate | 2016-05-31^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e22b13a26d73e521e3b19bdbda51b57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93b0e283cffaafbb40017f7af35e1416 |
| publicationDate | 2017-04-26^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CY-1117612-T1 |
| titleOfInvention | A METHOD FOR THE PREPARATION OF THE DETERMINATED ESTE OF DY- (2-THYNYLYL) GLUCIC ACID, AN INTERMEDIATE UNION IN THE SYNTHESIS OF BROOM |
| abstract | The present invention relates to a process for the preparation of the formula II tiotropium bromide comprising the following steps: (a) preparing the scopin ester of the formula I by converting the methyl bis (2-thienyl) glycolate to the formula IV; type III scopin in the presence of a suboptimal amount of a stereochemically hindered base selected from the group of alkali salts of branched C3 to C5 alkoxides in an inert solvent; b) isolation of the scopin ester with formula I; conversion of the compound into quaternary scorpine ester of formula I with methyl bromide. |
| priorityDate | 2012-03-30^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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