http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-286878-B6
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba045776bcd32d32e3100da8dfce4e28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_16f935ea6cb9c8927f7e3255aa283c62 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D477-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-568 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D477-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D477-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-568 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-572 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-397 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 |
| filingDate | 1993-02-02^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97b2c66083d5975541071f89599f949c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfcdc75d8128c64076cc30e6894db857 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0631c97ffc513102259762cf2b2f0064 |
| publicationDate | 2000-07-12^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-286878-B6 |
| titleOfInvention | Carbapenems, process of their preparation, intermediates for their preparation, those carbapenems used for treating infections and pharmaceutical preparations |
| abstract | In the present invention there are disclosed carbapenems of the general formula I in which Re1 represents 1-hydroxyethyl group, 1-fluoroethyl group or hydroxymethyl group, Re2 represents a hydrogen atom or alkyl group containing 1 to 4 carbon atoms, Re3 represents a hydrogen atom or alkyl group containing 1 to 4 carbon atoms, Re4 and Re5 that can be the same or different are selected from a group comprising a hydrogen atom, a halogen atom, a cyano group, an alkyl group containing 1 to 4 carbon atoms, a nitro group, a hydroxy group a carboxyl group an alkoxyl group containing 1 to 4 carbon atoms, an alkoxycarbonyl group containing 1 to 4 carbon atoms in the alkoxy moiety, an aminosulfonyl group, an alkylaminosulfonyl group containing 1 to 4 carbon atoms in the alkyl moiety, dialkylaminosulfonyl group containing 1 to 4 carbon atoms in the alkyl moiety, a carbamoyl group, alkylcarbamoyl group containing 1 to 4 carbon atoms in the alkyl moiety, dialkylcarbamoyl group containing 1 to 4 carbon atoms in the alkyl moiety, a trifluoromethyl group, a sulfonic acid group, an amino group, an alkylamino group containing 1 to 4 carbon atoms in the alkyl moiety, dialkylamino group containing 1 to 4 carbon atoms in the alkyl moiety, an alkanoylamino group containing 1 to 4 carbon atoms in the alkanoyl moiety, alkanoyl-A-alkylamino group containing 1 to 4 carbon atoms in the alkanoyl moiety and 1 to 4 carbon atoms in the alkyl moiety, an alkanesulfonamide group containing 1 to 4 carbon atoms in the alkane moiety and alkyl-S-(O)in group containing 1 to 4 carbon atoms in the alkyl moiety, wherein a is 0, 1 or 2 with the proviso consisting in that in position ortho to the bond to -NRe3- neither hydroxy group nor carboxyl group is present, or pharmaceutically acceptable salt or in vivo hydrolyzable ester thereof. In the present invention there are also claimed a process for preparing the above specified compounds, intermediates used in their preparation, their use as therapeutic agents as well as pharmaceutical compositions in which these compounds are comprised. |
| priorityDate | 1992-02-04^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Showing number of triples: 1 to 320 of 320.