http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-290713-B6

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-24
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-04
filingDate 1995-04-14^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84e246a87e3d6394a26410d5ed4ae995
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b3f4e569f5dac154834b6981d68e517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5e6ccf1efeb9313a42e5eab594d097b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba3b0095c992057c865a9177c324b249
publicationDate 2002-09-11^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CZ-290713-B6
titleOfInvention Condensed bicyclic thiophene derivatives, processes for their preparation, pharmaceutical compositions containing them and their use
abstract Derivatives of Formula I wherein all substituents are of particular interest. In the process for their preparation, a derivative of the formula Ia or a salt thereof is reacted with a compound of the formula H-NR.sup.22.nRsup.23.n., Or a salt thereof, in a solvent which does not cause an undesirable effect on the reaction in the presence of a base, and the resulting product is isolated by recrystallization, distillation or chromatography and optionally converted to its salt. The pharmaceutical composition containing them antagonizes the gonadotropin releasing hormone. It is used to prevent or treat sex hormone-dependent diseases such as prostate, uterine, breast, benign prostate hypertrophy, uterine fibroids, mucosa adenoma, prostatauxa, uterine inflammation, premature puberty, for conception control, menstrual cycle control, and contraception .à
priorityDate 1994-04-19^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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