abstract |
The invention relates to the preparation of a novel hydroxyiminosubstituted aminoacetonitrile, which is used as an intermediate for the preparation of substituted 2-Aminopyrazinverbindungen. According to the invention, an aminoacetonitrile of the formula I in which R & exp1! is a hydrogen or an alkyl group having 1 to 4 carbon atoms, with an alpha-chloro or alpha-bromoxime of the formula II, wherein X is chlorine or bromine, R & exp 2! Is hydrogen, halogen, an alkyl group having 1 to 3 carbon atoms or a trifluoromethyl group, n is the number 0, 1 or 2 and R & exp 3! is an alkyl group having 1 to 4 carbon atoms, reacted in a solvent in the presence of an acid-binding agent. |