| abstract |
The invention relates to a process for the preparation of 5-substituted oxazolidine-2,4-diones having hypoglycaemic activity for the treatment of diabetes. The aim of the invention is to provide compounds having improved hypoglycaemic activity which do not cause undesirable side effects. According to the invention, 5-substituted oxazolidine-2,4-diones, in particular 5-furyl, 5-thienyl, 5-chromanyl, 2,3-dihydro-5-benzene-1,3-furanyl, 5-pyridyl, 5-quinolyl , 5-pyrrolyl, 5-indolyl, 5-thiazolyl, 5-oxazolyl, 5-isothiazolyl and 5-isoxazolidine-2,4-diones and their pharmaceutically acceptable salts, as well as certain 3-acylated derivatives. |